Another Reason To Be Happy

I’m happy to announce the website for the book should be up by July 1:

This morning I found another reason for those of us with Chronic Kidney Disease to be happy.  I know!  It sounds ridiculous.  Now that that’s out of the way, there’s seemingly always been the suspicion that physical illness and depression were connected.  However, which came first?  We have sort of a chicken and the egg situation here.  This article from March 11’s ScienceDaily may help you understand the connection.

I left the usual reference topics in the article so you could see for yourself how to track down articles of interest to CKD patients by following the links.  Usually, you just click on whichever topic interests you.  You can’t do that here since I’ve reproduced the article from another site.  But, you can use the following link to go back to the original article to click through on these links:

Depression May Increase the Risk of Kidney Failure

ScienceDaily (Mar. 11, 2011)
— Depression is associated with an increased risk of developing kidney failure in the future, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology(CJASN). Approximately 10% of the US population will suffer from depression at some point during their lifetime.

See Also:
Lead investigator, Dr. Willem Kop (Department of Medical Psychology and Neuropsychology at the University of Tilburg, the Netherlands) and colleagues studied 5,785 people from four counties across the United States for 10 years. The participants were 65 years and older and not yet on dialysis. They completed a questionnaire measuring depressive symptoms and a broad range of medical measurements, including estimated glomerular filtration rate (eGFR) and risk factors for kidney and heart
diseases. The investigators examined whether depression predicted the onset of kidney disease or other medical problems in which the kidneys play a critical role.

According to the results, depression coincided with the presence of chronic kidney disease (CKD) and was 20% more common in individuals with kidney disease than those without kidney disease. The study shows that depression predicted subsequent rapid decline in kidney function, new onset clinically severe kidney disease (or end-stage renal disease), and  hospitalizations that were complicated by acute kidney injury. When the investigators corrected for the long-term effects of other medical
measures, the predictive value of depression for hospitalizations with acute kidney injury remained high.

Take home message: “People with elevated depressive symptoms have a higher risk of subsequent adverse kidney disease outcomes. This is partially explained by other medical factors related to depression and kidney disease. But, the association with depression was stronger in patients who were otherwise healthy compared to those who had co-existing medical disorders such as diabetes or heart disease,” explains Kop.

The investigators are currently analyzing which factors may explain the association with depression, which could include delayed seeking of medical care and miscommunications between patient and physicians and important biological processes associated with depression, such as the immune and nervous systems.

Study co-authors include Stephen Seliger (University of Maryland, Nephrology); Jeffrey Fink (University of Maryland Medical System, Department of Medicine, Division of Nephrology); Ronit Katz (University of Washington, Biostatistics); Michelle Odden (University of California,  Berkeley, Department of Epidemiology); Linda Fried (Veterans Affairs Pittsburgh Health System); Dena Rifkin (UCSD and VASDHS, Medicine); Mark Sarnak (Tufts-New England Medical Center, Medicine); and John Gottdiener (University of Maryland, School of Medicine, Medicine).

Story Source:

The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by American Society of Nephrology, via EurekAlert!, a service of AAAS.

Journal Reference:

  1. Willem J. Kop, Stephen L. Seliger, Jeffrey C. Fink, Ronit Katz,
    Michelle C. Odden, Linda F. Fried, Dena E. Rifkin, Mark J. Sarnak, John
    S. Gottdiener. Longitudinal Association of Depressive Symptoms with Rapid Kidney Function Decline and Adverse Clinical Renal Disease Outcomes. Clinical Journal of the American Society Nephrology, 2011; DOI: 10.2215/CJN.03840510

Since I am almost 65 years and not yet on dialysis, I’ll use this as the excuse I’ve been looking for to remain a Pollyanna and laugh at my woes.  How bad can they be?  I’m not dead and that’s worth a bunch of laughter.  I always use laughter.  It’s sustained me in the very worse of times with dear one’s illnesses and now my own.  As they used to say in some commercial: try it, you’ll like it.

Excuse me, my neighbor installing the new dog door just told me he found black mold in the old one.  I’ve got to go laugh.
Until Tuesday,
Keep living your life!

Published in: on June 21, 2011 at 12:00 pm  Leave a Comment  

The URI to TrackBack this entry is:

RSS feed for comments on this post.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s

%d bloggers like this: